STEM CELL
STEM CELL IV – REGENERATE
The discovery of stem cell therapy gave a new light of hope in the health industry and a new area for scientists to explore. The potential of their therapeutic potential, promises sustainable cures for previously untreated diseases. Stem cells may broadly be classified into totipotent, pluripotent, and multipotent, and each of these classes show enormous therapeutic functions.
Totipotent stem cells, however, out of all the other types, have become an ideal approach to deal with the therapies related to the diseases.
Totipotent stem cells are transiently occurring in vivo cells that can form all cell types of the embryo including the placenta, all mature cell types–differentiate into 200 cell types of the body and also can reconstitute a stem cell-deprived organ, thereby opening ways to tissue regeneration and replacement therapies respectively. It is considered the most versatile of the stem cell types.
The therapy whereby the totipotent stem cells are used to be infused into the human body will be differentiated into the desired cells based on what our body needs to restore the functions of the tissue.
Stem cells remain in the body throughout life. Our bodies depend on those stem cells to keep us healthy and to repair damage of any kind, whether from injury, illness, or neurological conditions. However, as we get older second by second, the stem cells inside our body will be reduced continuously.
STEM CELL – HEPATIC
Also known as liver stem cells or liver progenitor cells, are a type of stem cell found in the liver that can differentiate into various cell types that make up the liver, such as hepatocytes (the primary functional liver cells) and cholangiocytes (cells that line the bile ducts). Here are some key points about hepatic stem cells:
Role in Liver Regeneration: Hepatic stem cells play a crucial role in the liver’s ability to regenerate after injury or damage. They can activate and proliferate to replace lost or damaged liver cells, helping to maintain liver function.
Location: These stem cells are primarily located in the ductal regions of the liver and can also be found in the portal areas.
Potential for Therapy: Research into hepatic stem cells is ongoing, particularly regarding their potential for regenerative medicine. They may be explored for treating liver diseases, such as cirrhosis, acute liver failure, and liver cancer.
Differentiation: Hepatic stem cells can differentiate into multiple cell types in the liver, which makes them a focus of study for understanding liver development and repair mechanisms.
Challenges: While promising, the use of hepatic stem cells in clinical settings faces challenges, including efficient isolation, culture, and controlled differentiation, as well as potential risks related to tumor formation.
Overall, hepatic stem cells represent a significant area of research in both basic science and therapeutic applications related to liver health and disease.
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