Umbilical Cord Mesenchymal Stem Cells (UC-MSCs) are highly regenerative cells with self-renewal capabilities and the ability to differentiate into various cell types, including nerve, muscle, and bone cells. UC-MSCs are abundantly found in Wharton’s jelly within the umbilical cord and are considered more immature than mesenchymal stem cells derived from bone marrow. This makes them less immunogenic and gives them broader therapeutic potential.
Studies have shown that UC-MSCs play a role in tissue repair and regeneration and exhibit strong biological activity in inhibiting tumor cell growth and migration. Additionally, UC-MSCs support the hematopoietic microenvironment, enhance stem cell transplant success, and hold potential in treating hematological diseases and neurological disorders. Various neurotrophic factors, such as Vascular Endothelial Growth Factor (VEGF), Glial cell line-Derived Neurotrophic Factor (GDNF), and Brain-Derived Neurotrophic Factor (BDNF), secreted by UC-MSCs, contribute to nerve cell growth and accelerate the healing process.
With their multi-directional differentiation capabilities and immunomodulatory effects, UC-MSCs have emerged as a leading candidate in regenerative therapy, transplantation, and the treatment of various medical conditions with limited treatment options.
With their multi-directional differentiation capabilities and immunomodulatory effects, UC-MSCs have emerged as a leading candidate in regenerative therapy, transplantation, and the treatment of various medical conditions with limited treatment options.
Its key areas of potential include:
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